BDBM23420 7,4′-Dihydroxy-isoflavone (3a)::7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL8145::Daidzein::US20240398793, Compound 11::US8552057, 7

SMILES: c1cc(ccc1C2=COc3cc(ccc3C2=O)O)O

InChI Key: InChIKey=ZQSIJRDFPHDXIC-UHFFFAOYSA-N

Data: 8 KI  40 IC50  1 Kd  1 Other

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 23420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Mouse)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sulfotransferase 1A1 (Rat)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
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Sulfotransferase 2A1 (Rat)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxyacyl-[acyl-carrier-protein] dehydratase (malaria parasite P. falciparum)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-glucuronosyltransferase 1A1 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 1A1 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase, mitochondrial (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-amylase 1A (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	6.0	22
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Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	23
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	23
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Leukotriene A-4 hydrolase (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor beta (Sheep)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
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Neuraminidase (Influenza A virus)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Neuraminidase (Influenza A virus)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Neuraminidase (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Neuraminidase (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL62 (Baker's yeast)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B10 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proteasome subunit beta type-5 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde dehydrogenase, mitochondrial (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-glucuronidase (Escherichia coli (strain K12))	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-glucuronidase (Rat)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20	-11.4	n/a	n/a	n/a	n/a	n/a	n/a	25
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Carbonic anhydrase 12 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		56	-9.89	n/a	n/a	n/a	n/a	n/a	n/a	25
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Estrogen receptor beta (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		719	-8.37	n/a	n/a	n/a	n/a	n/a	n/a	25
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Estrogen receptor (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	n/a	25
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Carbonic anhydrase 2 (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	n/a	25
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Aromatase (Human)	BDBM23420 (CHEMBL8145 | US8552057, 7 | 7-hydroxy-3-(4-hydroxy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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