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BDBM26517 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine::Propargyl inhibitor, 15::Propargyl-linked, 9

SMILES: COc1ccc(OC)c(CC#Cc2cnc(N)nc2N)c1

InChI Key: InChIKey=UVQNCTDTAXLPKN-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26517
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydrofolate reductase (Bacillus anthracis)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Yeast)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Yeast)	BDBM26517 (5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]pyrimidin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair