BDBM26518 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine::Propargyl inhibitor, 16::Propargyl-linked, 10

SMILES: COc1ccc(OC)c(CC#Cc2c(C)nc(N)nc2N)c1

InChI Key: InChIKey=OEYXETAXVXPYMF-UHFFFAOYSA-N

Data: 1 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 26518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Bacillus anthracis)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Yeast)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Yeast)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bacillus anthracis)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bacillus anthracis)	BDBM26518 (Propargyl-linked, 10 | 5-[3-(2,5-dimethoxyphenyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair