BDBM293058 US10106501, Example AG1::cis-3-(2,4-dichloro-3-((6-cyano-1,4-dimethyl-1H-indol-2-yl)methyl)phenoxy)cyclopentanecarboxylic acid

SMILES Cc1cc(cc2n(C)c(Cc3c(Cl)ccc(O[C@H]4CC[C@H](C4)C(O)=O)c3Cl)cc12)C#N

InChI Key InChIKey=GWMOUDSPJATIPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293058   

TargetNuclear receptor ROR-gamma(Human)
Abbvie

US Patent
LigandPNGBDBM293058(cis-3-(2,4-dichloro-3-((6-cyano-1,4-dimethyl-1H-in...)
Affinity DataIC50: 750nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
US Patent