BDBM35743 CHEMBL479863::cis-1,2-diaminocyclohexane derivative, A

SMILES: CN(C)C(=O)[C@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

InChI Key: InChIKey=SZBHQQIIGORYND-UHFFFAOYSA-N

Data: 7 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 35743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	23
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Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	23
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Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Rabbit)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		1.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		2.85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Rat)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		8.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		2.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		6.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII (Human)	BDBM35743 (CHEMBL479863 | cis-1,2-diaminocyclohexane derivati...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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