BDBM50006803 2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoquinone::CHEMBL82479::CV-6504

SMILES Cc1c(O)c(=Cc2cccnc2)c(C)c(O)c1=C

InChI Key InChIKey=ORBJSXMIMYMLQQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006803   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
Affinity DataIC50:  680nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
Affinity DataIC50:  62nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
Affinity DataIC50:  400nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed