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BDBM50009385 1,4-butylenediamine::1,4-tetramethylenediamine::CHEMBL46257::H2N(CH2)4NH2::Putrescin::Putreszin::Tetramethylendiamin::butane-1,4-diamine::butylenediamine::putrescina::putrescine

SMILES: NCCCCN

InChI Key: InChIKey=KIDHWZJUCRJVML-UHFFFAOYSA-N

Data: 2 KI  1 IC50

PDB links: 40 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009385   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009385
PNG
(1,4-butylenediamine | 1,4-tetramethylenediamine | ...)
Show InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
PDB
MMDB

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CHEBI
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PC sid
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Article
PubMed
3.30E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Ornithine Decarboxylase (ODC) isolated from the livers of thioactamide treated rats.


J Med Chem 33: 1969-74 (1990)


Article DOI: 10.1021/jm00169a025
BindingDB Entry DOI: 10.7270/Q2MG7NH8
More data for this
Ligand-Target Pair
Phosphodiesterase 1


(Bos taurus-BOVINE)
BDBM50009385
PNG
(1,4-butylenediamine | 1,4-tetramethylenediamine | ...)
Show InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
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Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Universit£ Rennes 1

Curated by ChEMBL


Assay Description
Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesterase


J Med Chem 49: 232-45 (2006)


Article DOI: 10.1021/jm050018q
BindingDB Entry DOI: 10.7270/Q21Z4757
More data for this
Ligand-Target Pair
Ornithine decarboxylase


(Rattus norvegicus)
BDBM50009385
PNG
(1,4-butylenediamine | 1,4-tetramethylenediamine | ...)
Show InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
PDB
MMDB

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CHEBI
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Article
PubMed
3.50E+6n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of liver Ornithine decarboxylase in thioacetamide-treated rat


J Med Chem 38: 4337-41 (1995)


Article DOI: 10.1021/jm00021a024
BindingDB Entry DOI: 10.7270/Q23N241Z
More data for this
Ligand-Target Pair