BDBM50012070 5-Hydroxy-2-methyl-[1,4]naphthoquinone::5-hydroxy-2-methylnaphthalene-1,4-dione::CHEMBL295316::Plum-bagin::Plumbagin (6b)::Pumbagin::plumbagin

SMILES: CC1=CC(=O)c2c(cccc2O)C1=O

InChI Key: InChIKey=VCMMXZQDRFWYSE-UHFFFAOYSA-N

Data: 21 IC50  2 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50012070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase KAT2B (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase p300 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase p300 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 14 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division protein FtsZ (Bacillus subtilis)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a
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Trypanothione reductase (Trypanosoma cruzi)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
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Trypanothione reductase (Trypanosoma cruzi)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase p300 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase KAT2B (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone acetyltransferase p300 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] A (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
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Co-chaperonin GroES (Escherichia coli)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Thiosulfate sulfurtransferase (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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60 kDa heat shock protein, mitochondrial (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Chaperonin GroEL (Escherichia coli)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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M-phase inducer phosphatase 1 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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M-phase inducer phosphatase 2 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 7 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase (Human)	BDBM50012070 (CHEMBL295316 | plumbagin | 5-hydroxy-2-methylnapht...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
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