BDBM50014872 (-)-demecolcine::(S)-1,2,3,10-tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one::1,2,3,10-Tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one::1,2,3,10-Tetramethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one (Demecolcine)::CHEMBL312862::Demecolcine::Demicolcine::cid_220401::colcemide

SMILES: CN[C@H]1CCc2cc(c(c(c2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

InChI Key: InChIKey=NNJPGOLRFBJNIW-UHFFFAOYSA-N

Data: 6 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50014872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor coactivator 3 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tegument protein VP16 (HHV-1)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor coactivator 1 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 0 group B member 1 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>834	n/a	n/a	n/a	n/a	n/a	n/a
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Steroidogenic factor 1 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tubulin beta-2B chain (Bovine)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Rat)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50014872 (cid_220401 | 1,2,3,10-Tetramethoxy-7-methylamino-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a
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