BDBM50016490 (6aR,10aR)-7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline::7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline::7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline (Agroclavine)::CHEMBL449081::cid_73484

SMILES CN1CC(C)=C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13

InChI Key InChIKey=XJOOMMHNYOJWCZ-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016490   

Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50016490(7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-f...)
Affinity DataIC50: 140nMAssay Description:Tested for its binding affinity towards 5-hydroxytryptamine 1 receptor in rat cortical membrane homogenates using radioligand ([3H]5-HT) binding assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50016490(7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-f...)
Affinity DataIC50: 270nMAssay Description:Binding affinity at 5-hydroxytryptamine 2 receptor from rat frontal cortex homogenates by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50016490(7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-f...)
Affinity DataIC50: 890nMAssay Description:Competition in vitro with the dopamine receptor D2 antagonist [3H]spiperone, for binding sites on calf caudate membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50016490(7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-f...)
Affinity DataEC50:  8.67E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50016490(7,9-Dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-f...)
Affinity DataEC50:  1.12E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay