BDBM50017550 CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole

SMILES: CCCNC1CCc2nc(N)sc2C1

InChI Key: InChIKey=FASDKYOPVNHBLU-UHFFFAOYSA-N

Data: 23 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50017550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Bovine)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		955	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		8.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2C (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Guinea pig)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50017550 (Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair