BDBM50018011 Aubagio::CHEBI:68540::HMR-1726::TERIFLUNOMIDE

SMILES: C/C(=C(\C#N)/C(=O)Nc1ccc(cc1)C(F)(F)F)/O

InChI Key: InChIKey=UTNUDOFZCWSZMS-UHFFFAOYSA-N

Data: 24 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50018011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Rat)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Mouse)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	408	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a
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Calcium release-activated calcium channel protein/Stromal interaction molecule 1 (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Rat)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Mouse)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Blood fluke)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	312	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Blood fluke)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Human)	BDBM50018011 (CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair