BDBM50028166 CHEMBL934::METYRAPONE::US9138393, Metyrapone::US9144538, Metyrapone::US9394290, MTP (metyrapone)

SMILES: CC(C)(c1cccnc1)C(=O)c2cccnc2

InChI Key: InChIKey=FJLBFSROUSIWMA-UHFFFAOYSA-N

Data: 1 KI  32 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50028166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rat)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rat)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rat)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Bovine)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Human)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Bovine)	BDBM50028166 (CHEMBL934 | METYRAPONE | US9138393, Metyrapone | U...) Show SMILES Show InChI	GoogleScholar	UniChem		580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair