BDBM50028166 CHEMBL934::METYRAPONE::US9138393, Metyrapone::US9144538, Metyrapone::US9394290, MTP (metyrapone)
SMILES CC(C)(C(=O)c1cccnc1)c1cccnc1
InChI Key InChIKey=FJLBFSROUSIWMA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50028166
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human steroid-11beta-hydroxylase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Saarland University & Helmholtz Institute For Pharmaceutical Research Saarland
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair