BDBM50037996 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine::CHEMBL51173::N-[(R)-1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide::N-[1-(4-Carbamimidoyl-benzyl)-2-(3,4-dihydro-2H-pyridin-1-yl)-2-oxo-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide::N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide::N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide(NAPAP)
SMILES NC(=N)c1ccc(C[C@@H](NC(=O)CNS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2)cc1
InChI Key InChIKey=XXTWZTPVNIYSJZ-XMMPIXPASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50037996
Affinity DataKi: 4nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 6nMAssay Description:The compound was evaluated in vitro for the thrombin inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory Activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibitory activity against human thrombin (using Chromozym TH as the substrate)More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 325nMAssay Description:Inhibitory effect of compound was measured in bovine trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 690nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
Affinity DataKi: 690nMAssay Description:Inhibitory activity against human trypsin (using Chromozym TH as the substrate)More data for this Ligand-Target Pair
Affinity DataKi: 690nMAssay Description:Inhibitory Activity against bovine beta-trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 690nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Binding affinity against bovine ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Inhibitory Activity against bovine Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+3nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibitory activity against Plasmin.More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Klinikum Der Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
Affinity DataEC50: 750nMAssay Description:Effective concentration against thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro trypsin inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 169nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:In vitro thrombin inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Antithrombin III (ATIII)-mediated anti-Xa activity was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair