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Found 22 Enz. Inhib. hit(s) with Target = 'Trypsin-3'
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50421510(CHEMBL239127)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for inhibition of bovine beta trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449678(CHEMBL4164510)
Affinity DataKi:  26nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449679(CHEMBL4167071)
Affinity DataKi:  28nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449677(CHEMBL4172393)
Affinity DataKi:  35nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449680(CHEMBL4170662)
Affinity DataKi:  38nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449683(CHEMBL4172833)
Affinity DataKi:  45nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449676(CHEMBL4162159)
Affinity DataKi:  134nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449682(CHEMBL4176209)
Affinity DataKi:  335nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449675(CHEMBL4175285)
Affinity DataKi:  369nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50449681(CHEMBL4165595)
Affinity DataKi:  402nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  690nMAssay Description:Inhibitory Activity against bovine beta-trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50124947(CHEMBL453539)
Affinity DataKi:  4.96E+3nMAssay Description:Competitive inhibition of recombinant human mesotrypsin using Z-GPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50387180(CHEMBL2047998)
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50387183(CHEMBL2048000)
Affinity DataKi:  4.76E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50387182(CHEMBL2048003)
Affinity DataKi:  7.94E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50387181(CHEMBL2047999)
Affinity DataKi:  1.09E+6nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataIC50:  1nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50131981(CHEMBL340098 | N-{[1-(Benzothiazole-2-carbonyl)-4-...)
Affinity DataIC50:  2nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50131976(1-Acetyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataIC50:  4nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50131984(1-Acetyl-azetidine-2-carboxylic acid [1-(benzothia...)
Affinity DataIC50:  5nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50131978(1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataIC50:  8nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed