BDBM50039994 CHEMBL419898::[(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)NCC

InChI Key InChIKey=GWLZMBFVBYHGBD-ZVAWYAOSSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50039994   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  42nMAssay Description:Tested for inhibitory activity on porcine calpain 2 from kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Bos taurus)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  50nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  66nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  73nMAssay Description:Tested for inhibitory activity on human calpain 2 from placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  78nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994(CHEMBL419898 | [(S)-1-(1-Ethylcarbamoyl-butylcarba...)
Affinity DataKi:  78nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed