BDBM50043348 1,8-Dihydroxy-10-(4-nitro-benzylidene)-10H-anthracen-9-one::1,8-dihydroxy-10-(4-nitrobenzylidene)anthracen-9(10H)-one::CHEMBL337845

SMILES [#8]-c1cccc2\[#6](=[#6]\c3ccc(cc3)-[#7+](-[#8-])=O)-c3cccc(-[#8])c3-[#6](=O)-c12

InChI Key InChIKey=ITRWJABLTBZJPV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043348   

Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043348(1,8-Dihydroxy-10-(4-nitro-benzylidene)-10H-anthrac...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50043348(1,8-Dihydroxy-10-(4-nitro-benzylidene)-10H-anthrac...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043348(1,8-Dihydroxy-10-(4-nitro-benzylidene)-10H-anthrac...)
Affinity DataIC50:  1.40E+4nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed