BDBM50044499 5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL87129

SMILES CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=AJQSTGRQYVWHEA-UHFFFAOYSA-N

Data  3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50044499   

TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044499(5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-y...)
Show SMILES CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H29N7O/c1-3-4-12-26-31-35(19-22-9-7-8-20(2)17-22)28(36)34(26)18-21-13-15-23(16-14-21)24-10-5-6-11-25(24)27-29-32-33-30-27/h5-11,13-17H,3-4,12,18-19H2,1-2H3,(H,29,30,32,33)
Affinity DataIC50: 12nMAssay Description:In vitro antagonistic activity for angiotensin II receptor, type 1 by displacing 125I[Sar, ILe8 ]AII radioligand in rabbit aorta membrane without usi...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044499(5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-y...)
Show SMILES CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H29N7O/c1-3-4-12-26-31-35(19-22-9-7-8-20(2)17-22)28(36)34(26)18-21-13-15-23(16-14-21)24-10-5-6-11-25(24)27-29-32-33-30-27/h5-11,13-17H,3-4,12,18-19H2,1-2H3,(H,29,30,32,33)
Affinity DataIC50: 1.20E+10nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044499(5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-y...)
Show SMILES CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C28H29N7O/c1-3-4-12-26-31-35(19-22-9-7-8-20(2)17-22)28(36)34(26)18-21-13-15-23(16-14-21)24-10-5-6-11-25(24)27-29-32-33-30-27/h5-11,13-17H,3-4,12,18-19H2,1-2H3,(H,29,30,32,33)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at angiotensin 2 type-1 receptor in Oryctolagus cuniculus (rabbit) aorta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails Article