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BDBM50049066 2-Hydroxynaphthoquinone::CHEBI:44401::Lawsone::NSC-8625

SMILES: c1ccc2c(c1)C(=O)C=C(C2=O)O

InChI Key: InChIKey=CSFWPUWCSPOLJW-UHFFFAOYSA-N

Data: 6 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049066
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
P2X purinoceptor 7 (Mouse)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Blood fluke)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SETD7 (Human)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM50049066 (CHEBI:44401 \| 2-Hydroxynaphthoquinone \| Lawsone \| ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair