BDBM50052254 2',6'-dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (3)::CHEMBL3318469

SMILES: OC1=C(Sc2ccccc2Cl)C(=O)CC(C1)c1c(Cl)cccc1Cl

InChI Key: InChIKey=WOBNNXBIQRYYDO-UHFFFAOYSA-N

Data: 13 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50052254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
L-lactate dehydrogenase A chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
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L-lactate dehydrogenase B chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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L-lactate dehydrogenase B chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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L-lactate dehydrogenase A chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
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L-lactate dehydrogenase A chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Malate dehydrogenase, cytoplasmic (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Malate dehydrogenase, mitochondrial (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase A chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase A chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
L-lactate dehydrogenase B chain (Human)	BDBM50052254 (2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair