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Found 3 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase B chain' and Ligand = 'BDBM50052254'
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)
Affinity DataIC50:  4.40E+3nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM50052254(2',6'-dichloro-4-((2-chlorophenyl)thio)-5-...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed