BDBM50065258 (2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol::(2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol::CHEMBL314772::Fucosidase Inhibitor, 3

SMILES: C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O

InChI Key: InChIKey=VYOCYWDJTQRZLC-UHFFFAOYSA-N

Data: 10 KI  6 IC50  4 Kd  4 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50065258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-fucosidase-like protein (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	27	n/a	n/a	n/a	6.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bovine)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Rat)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bovine)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-fucosidase-like protein (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	372	n/a	n/a	n/a	8.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-fucosidase-like protein (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	55.1	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-fucosidase-like protein (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14.8	n/a	n/a	n/a	6.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bovine)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bovine)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Plasma alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Human)	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 4 hits for monomerid = 50065258

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Alpha-fucosidase (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)	GoogleScholar			-10.7	0.0530	-10.2	n/a	6	-236
TBA					Details of this binding reaction
Alpha-fucosidase (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)	GoogleScholar			-10.0	-0.513	-14.7	n/a	6.5	-236
TBA					Details of this binding reaction
Alpha-fucosidase (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)	GoogleScholar			-10.0	-0.680	-15.6	n/a	6.5	-236
TBA					Details of this binding reaction
Alpha-fucosidase (Bacteroides thetaiotaomicron )	BDBM50065258 (CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,...)	GoogleScholar			-8.84	-0.566	-13.4	n/a	6.5	-236
TBA					Details of this binding reaction