BDBM50070597 2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-piperidin-4-ylmethoxy)-5-methyl-phenyl ester::CHEMBL41876
SMILES Cc1cc(OCC2CCN(CC2)C(N)=N)cc(OS(=O)(=O)c2ccccc2Cl)c1
InChI Key InChIKey=CYPTUCSRAKRHJR-UHFFFAOYSA-N
Data 11 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50070597
Affinity DataKi: 4.60nMAssay Description:Compound was evaluated for inhibition of ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Anti- Thrombin activity using standard chromogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease trypsin using benzoyl-Phe-Val-Arg-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Compound was evaluated for inhibition of Serine protease chymotrypsinMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Compound was evaluated for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+4nMAssay Description:Compound was evaluated for inhibition of TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease factor Xa using benzoyl-Ile-Glu-Gly-Arg-p-nitroanilide as substrateMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
3-Dimensional Pharmaceuticals
Curated by ChEMBL
3-Dimensional Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease urokinase using carbobenzyloxy-Phe-Val-Arg-pnitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease chymotrypsin using suc-Ala-Ala-Pro-Phe-p-nitroanilide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease plasmin using tosyl-Gly-Pro-Lys-p-nitroanilide as substrateMore data for this Ligand-Target Pair