BDBM50073762 CHEMBL366734::{(R)-1-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-2-yl]-pyrrolidin-2-yl}-methanol

SMILES CCn1cnc2c(Nc3cccc(Cl)c3)nc(nc12)N1CCC[C@@H]1CO

InChI Key InChIKey=INOQUZXUCBEROH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073762   

TargetCyclin-dependent kinase 1(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073762({(R)-1-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Cyclin-dependent kinase 1, CDK1-related human bladder carcinoma (T24) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073762({(R)-1-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-...)
Affinity DataIC50: 3.85E+4nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Human)
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50073762({(R)-1-[6-(3-Chloro-phenylamino)-9-ethyl-9H-purin-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed