BDBM50080528 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide::4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione::CHEMBL123292::Cycloheximid::Zykloheximid::cid_6197::cycloheximide::med.21724, Compound Cycloheximide

SMILES: C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C

InChI Key: InChIKey=YPHMISFOHDHNIV-UHFFFAOYSA-N

Data: 7 KI  8 IC50  3 EC50

PDB links: 18 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50080528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
COUP transcription factor 2 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tegument protein VP16 (HHV-1)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	189	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase FKBP1A (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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60S ribosomal protein L19-A (Baker's yeast)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	644	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic initiation factor 4A-I (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase FKBP1A (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase FKBP4 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase FKBP14 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		7.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase FKBP3 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.87E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Human)	BDBM50080528 (Cycloheximid | 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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