BDBM50094464 CHEMBL3590107::US10525036, Example SCH772984::US10934304, Example SCH772984

SMILES: O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1

InChI Key: InChIKey=HDAJDNHIBCDLQF-UHFFFAOYSA-N

Data: 25 IC50  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50094464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0501	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase 3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 6 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1/3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1/3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50094464 (CHEMBL3590107 | US10525036, Example SCH772984 | US...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair