BDBM50117632 CHEMBL3613609

SMILES CN(C)CC1(CCN(CC1)c1ncnc2[nH]cc(C)c12)C(=O)Nc1cccc(c1)C(=O)OCC#C

InChI Key InChIKey=HFBCKXXEXNDPEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50117632   

TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  16nMAssay Description:Inhibition of ROCK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 2(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Amakem Therapeutics

Curated by ChEMBL
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed