BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50127708 (1H)-indole-3-carbonitrile::1H-Indole-3-carbonitrile::CHEMBL46724

SMILES: c1ccc2c(c1)c(c[nH]2)C#N

InChI Key: InChIKey=CHIFTAQVXHNVRW-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127708
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Human)	BDBM50127708 (1H-Indole-3-carbonitrile \| (1H)-indole-3-carbonitr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Human)	BDBM50127708 (1H-Indole-3-carbonitrile \| (1H)-indole-3-carbonitr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Mouse)	BDBM50127708 (1H-Indole-3-carbonitrile \| (1H)-indole-3-carbonitr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 1/2 (Human)	BDBM50127708 (1H-Indole-3-carbonitrile \| (1H)-indole-3-carbonitr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair