BDBM50127708 (1H)-indole-3-carbonitrile::1H-Indole-3-carbonitrile::CHEMBL46724
SMILES N#Cc1c[nH]c2ccccc12
InChI Key InChIKey=CHIFTAQVXHNVRW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50127708
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1/2(Homo sapiens (Human))
Roche Discovery Welwyn
Curated by ChEMBL
Roche Discovery Welwyn
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair