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BDBM50137284 2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL146289
SMILES: ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1ccccc1
InChI Key: InChIKey=NOENPCOHNDAVLW-UHFFFAOYSA-N
Data: 8 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Matrix metalloproteinase-9 (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 335 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-14 (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-15 (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 218 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-16 (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interstitial collagenase (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 6.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage metalloelastase (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 421 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-26 (Human) | BDBM50137284![]() (2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...) | GoogleScholar | UniChem | n/a | n/a | 858 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||