BDBM50137284 2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL146289

SMILES ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=NOENPCOHNDAVLW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137284   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  335nMAssay Description:Inhibition of matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of matrix metalloproteinase-14 (MMP-14)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  218nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  858nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  6.32E+3nMAssay Description:Inhibition of matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  421nMAssay Description:Inhibition of matrix metalloproteinase-12 (MMP-12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  430nMAssay Description:Inhibition of matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)
Affinity DataIC50:  184nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed