BDBM50140803 4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carboxylic acid pyridin-3-ylamide::CHEMBL280981
SMILES Fc1ccc(CCN2CCN(CC2)c2ncnc3c(C(=O)Nc4cccnc4)c4CCCCn4c23)cc1F
InChI Key InChIKey=YEHNDLQWKSUNTD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50140803
Affinity DataIC50: 76nMAssay Description:Inhibitory activity against human transporter MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 9.73E+3nMAssay Description:Inhibitory concentration to inhibit MRP1 in CYP 3A4 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 235nMAssay Description:Effective concentration of the compound to inhibit MRP1 in potentiation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibitory activity against mouse transporter Pgp (P-glycoprotein) expressed in EMT6/AR1.0 cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:Inhibitory concentration against multidrug resistance associated protein 1More data for this Ligand-Target Pair