BDBM50140803 4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carboxylic acid pyridin-3-ylamide::CHEMBL280981

SMILES Fc1ccc(CCN2CCN(CC2)c2ncnc3c(C(=O)Nc4cccnc4)c4CCCCn4c23)cc1F

InChI Key InChIKey=YEHNDLQWKSUNTD-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140803   

TargetMultidrug resistance-associated protein 1(Mus musculus)
Xenova

Curated by ChEMBL
LigandPNGBDBM50140803(4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-y...)
Affinity DataEC50:  235nMAssay Description:Effective concentration of the compound to inhibit MRP1 in potentiation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed