BDBM50177015 CHEMBL3814206::US10144715, Compound 19-1

SMILES: CC(C)[C@@H]1CN(CCN1c2ncc(c(n2)C(F)(F)F)CO)c3ccc(c(c3)S(=O)(=O)C)CO

InChI Key: InChIKey=FPVIRRAMNBCEDK-UHFFFAOYSA-N

Data: 7 KI  12 IC50  6 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50177015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	244	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	608	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	244	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Retinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mineralocorticoid receptor (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha/LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha/LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM50177015 (CHEMBL3814206 | US10144715, Compound 19-1) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair