BDBM50204693 3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (pyridin-4-ylmethyl)-amide::CHEMBL242753

SMILES: Oc1ccc(cc1)-c1ccc(cc1)-c1n[nH]c-2c1Cc1cc(ccc-21)C(=O)NCc1ccncc1

InChI Key: InChIKey=FTEBJMPQIWYFGP-UHFFFAOYSA-N

Data: 11 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50204693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.90E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C gamma type (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk2 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MARK2 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204693 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair