BDBM50240406 CHEMBL423288::N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)acetamide::N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-acetamide

SMILES: CC(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key: InChIKey=PMGVYOWQUQXHSP-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50240406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50240406 (N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair