BDBM50262939 2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-5-(trifluoromethyl)-4(3H)-quinazolinone::CHEMBL476323

SMILES: Cc1nc2cccc(c2c(=O)n1-c1ccc(OCCCN2CCCC2)cc1)C(F)(F)F

InChI Key: InChIKey=DDDZBLNULGDPGA-UHFFFAOYSA-N

Data: 7 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50262939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		0.531	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine receptor H3 (Rhesus macaque)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Rat)	BDBM50262939 (2-Methyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}pheny...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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