BDBM50314776 CHEMBL1089865::N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methylbenzamide

SMILES: Cc1ccc(cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O)C(=O)NC1CC1

InChI Key: InChIKey=BTFCCPKDGZFGPR-UHFFFAOYSA-N

Data: 4 KI  8 IC50  4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50314776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 13 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM50314776 (N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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