BDBM50324678 CHEMBL1222314::thiophene-2-carboxylic acid

SMILES OC(=O)c1cccs1

InChI Key InChIKey=QERYCTSHXKAMIS-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324678   

TargetBeta-lactamase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50324678(CHEMBL1222314 | thiophene-2-carboxylic acid)
Affinity DataKi:  4.00E+7nMAssay Description:Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Tokushima University

Curated by ChEMBL
LigandPNGBDBM50324678(CHEMBL1222314 | thiophene-2-carboxylic acid)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human DAO using D-serine as substrate after 20 mins in presence of FADMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed