BDBM50336388 CHEMBL1668261::FXR_64::trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyridin-3-yl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)acetamido)cyclohexanecarboxylic acid

SMILES: COc1ccc(-c2nc3cc(F)c(F)cc3n2[C@@H](C2CCCCC2)C(=O)N[C@H]2CC[C@@H](CC2)C(O)=O)c(OC)n1

InChI Key: InChIKey=UBXGEZISKCURBV-UHFFFAOYSA-N

Data: 6 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50336388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	315	n/a	n/a	n/a	n/a	7.4	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50336388 (trans-4-((2S)-2-cyclohexyl-2-(2-(2,4-dimethoxypyri...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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