Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50336388'
TargetBile acid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336388(CHEMBL1668261 | FXR_64 | trans-4-((2S)-2-cyclohexy...)
Affinity DataIC50:  210nMAssay Description:Displacement of radioligand from human FXR by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336388(CHEMBL1668261 | FXR_64 | trans-4-((2S)-2-cyclohexy...)
Affinity DataIC50:  315nMpH: 7.4Assay Description:The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBile acid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336388(CHEMBL1668261 | FXR_64 | trans-4-((2S)-2-cyclohexy...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at Gal4-fused human FXR by luciferase reporter gene transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed