BDBM50399944 CHEMBL2181244

SMILES COc1ccccc1N(C)C(=O)c1cncnc1Oc1cc(Cl)ccc1Cl

InChI Key InChIKey=DWBDWTLBGPVCTD-UHFFFAOYSA-N

Data  1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399944   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399944(CHEMBL2181244)
Show SMILES COc1ccccc1N(C)C(=O)c1cncnc1Oc1cc(Cl)ccc1Cl
Show InChI InChI=1S/C19H15Cl2N3O3/c1-24(15-5-3-4-6-16(15)26-2)19(25)13-10-22-11-23-18(13)27-17-9-12(20)7-8-14(17)21/h3-11H,1-2H3
Affinity DataEC50:  160nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair