BDBM50400147 CHEMBL2179014

SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cnc(N[C@H]4CCOC4)nc1C1CCCC1)C(C3)C2

InChI Key InChIKey=VMTZDIHMLVWUQZ-CKAXPNCZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50400147   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400147(CHEMBL2179014)
Affinity DataIC50:  21nMAssay Description:Inhibition of human 11beta-HSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400147(CHEMBL2179014)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 17beta-HSD1 by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400147(CHEMBL2179014)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse 11beta-HSD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400147(CHEMBL2179014)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human 11beta-HSD1 by HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50400147(CHEMBL2179014)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed