BDBM50401351 CHEMBL2205807

SMILES Cc1ccc(nc1)-c1ccc(C)cn1

InChI Key InChIKey=PTRATZCAGVBFIQ-UHFFFAOYSA-N

Data  4 IC50  6 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50401351   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataIC50: 2.04E+5nMAssay Description:Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  2.51E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  1.58E+4nMAssay Description:Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  7.50E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  7.94E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataIC50: 2.00E+5nMAssay Description:Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataIC50: 2.00E+5nMAssay Description:Displacement of [125I]-CCL3 from human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  2.30E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataEC50:  1.70E+4nMAssay Description:Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50401351(CHEMBL2205807)
Show SMILES Cc1ccc(nc1)-c1ccc(C)cn1
Show InChI InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Affinity DataIC50: 2.06E+5nMAssay Description:Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrsMore data for this Ligand-Target Pair