BDBM50415420 CHEMBL592158

SMILES CN(C(=O)c1conc1-c1ccccc1Cl)c1ccc(Cl)cc1

InChI Key InChIKey=BGKSZURFTXDSNL-UHFFFAOYSA-N

Data  1 EC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415420   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50415420(CHEMBL592158)
Show SMILES CN(C(=O)c1conc1-c1ccccc1Cl)c1ccc(Cl)cc1
Show InChI InChI=1S/C17H12Cl2N2O2/c1-21(12-8-6-11(18)7-9-12)17(22)14-10-23-20-16(14)13-4-2-3-5-15(13)19/h2-10H,1H3
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair