BDBM50444890 CHEMBL235994

SMILES CCC(=C(c1ccc(OCCN2CCOCC2)cc1)c1ccc(OCCN2CCOCC2)cc1)c1ccccc1

InChI Key InChIKey=PLBYMFPIIYONEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444890   

TargetProteasome subunit beta type-5(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444890BDBM50444890(CHEMBL235994)
Affinity DataIC50: 7.19E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444890BDBM50444890(CHEMBL235994)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50444890BDBM50444890(CHEMBL235994)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed