BDBM50513995 BCX-4430::Bcx4430::Galidesivir

SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=AMFDITJFBUXZQN-KUBHLMPHSA-N

Data  8 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50513995   

TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in human Huh-7 cells assessed as antiviral activity by neutral dy...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human RD cells assessed as antiviral activity by neutral dye base...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human RD cells assessed as antiviral activity by neutral dye based col...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in human Huh-7 cells assessed as antiviral activity by neutral dye b...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in African green monkey Vero cells assessed as antiviral activity by neut...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC-59 infected in human HuH7 cells assessed as antiviral activity by neutral dye based c...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Ugandan MR-766 infected in African green monkey Vero cells assessed as antiviral activity by...More data for this Ligand-Target Pair
TargetGenome polyprotein(Zika virus)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513995(BCX-4430 | Bcx4430 | Galidesivir)
Show SMILES Nc1ncnc2c(c[nH]c12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3,5,7,9-10,13,16-19H,2H2,(H2,12,14,15)/t5-,7+,9-,10+/m1/s1
Affinity DataEC50:  1.43E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus Malaysian P 6-740 infected in African green monkey Vero cells assessed as antiviral activity...More data for this Ligand-Target Pair