BDBM5364 2-Anilino-5-aryloxazole 5::N,5-diphenyl-1,3-oxazol-2-amine::aminoxazole 24

SMILES N(c1ncc(o1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=HFICAVMUTYFODG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5364   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5364(2-Anilino-5-aryloxazole 5 | N,5-diphenyl-1,3-oxazo...)
Affinity DataIC50:  1.20E+3nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5364(2-Anilino-5-aryloxazole 5 | N,5-diphenyl-1,3-oxazo...)
Affinity DataIC50:  134nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed