BDBM81423 N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-1-yl]acetamide, Compound C

SMILES COc1ccc(NC(=O)Cn2c(nc3ccccc23)-c2cscn2)cc1

InChI Key InChIKey=MBQCZEPAGIDJLM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 81423   

TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50:  1.20E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Helicobacter pylori (strain G27))
Brandeis University

LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50:  600nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Borrelia burgdorferi)
Brandeis University

LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50:  600nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Brandeis University

Curated by ChEMBL
LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes)
Brandeis University

LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50:  7.00E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed